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Analysis of galectin expression in the spleen. A – D : Galectin-1 (Gal-1) immunoreactivity. E–H <t>:</t> <t>Galectin-3</t> <t>(Gal-3)</t> immunoreactivity. I–L : Galectin-9 (Gal-9) immunoreactivity. Immunolabeling is observed in both white pulp (wp) and red pulp (rp), with differences in distribution and intensity among groups: SHAM (control animals), MCP (animals treated with MCP), CIS (animals treated with cisplatin), and MCP + CIS (animals treated with MCP and cisplatin). Counterstain: Carazzi’s hematoxylin. Scale bars: 100 μm. M–O : Densitometric analysis of Gal-1, Gal-3, and Gal-9 immunoreactivity in splenic tissue. Data represent the mean ± SEM of arbitrary units (a.u.) of protein expression ( n = 5 animals/group). * p < 0.05; ** p < 0.01, *** p < 0.001; **** p < 0.0001 (M, O, Q-S: ANOVA followed by post-hoc Tukey test; N: Kruskal-Wallis followed by post-hoc Dunn’s test)
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Analysis of galectin expression in the spleen. A – D : Galectin-1 (Gal-1) immunoreactivity. E–H <t>:</t> <t>Galectin-3</t> <t>(Gal-3)</t> immunoreactivity. I–L : Galectin-9 (Gal-9) immunoreactivity. Immunolabeling is observed in both white pulp (wp) and red pulp (rp), with differences in distribution and intensity among groups: SHAM (control animals), MCP (animals treated with MCP), CIS (animals treated with cisplatin), and MCP + CIS (animals treated with MCP and cisplatin). Counterstain: Carazzi’s hematoxylin. Scale bars: 100 μm. M–O : Densitometric analysis of Gal-1, Gal-3, and Gal-9 immunoreactivity in splenic tissue. Data represent the mean ± SEM of arbitrary units (a.u.) of protein expression ( n = 5 animals/group). * p < 0.05; ** p < 0.01, *** p < 0.001; **** p < 0.0001 (M, O, Q-S: ANOVA followed by post-hoc Tukey test; N: Kruskal-Wallis followed by post-hoc Dunn’s test)
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Analysis of galectin expression in the spleen. A – D : Galectin-1 (Gal-1) immunoreactivity. E–H : Galectin-3 (Gal-3) immunoreactivity. I–L : Galectin-9 (Gal-9) immunoreactivity. Immunolabeling is observed in both white pulp (wp) and red pulp (rp), with differences in distribution and intensity among groups: SHAM (control animals), MCP (animals treated with MCP), CIS (animals treated with cisplatin), and MCP + CIS (animals treated with MCP and cisplatin). Counterstain: Carazzi’s hematoxylin. Scale bars: 100 μm. M–O : Densitometric analysis of Gal-1, Gal-3, and Gal-9 immunoreactivity in splenic tissue. Data represent the mean ± SEM of arbitrary units (a.u.) of protein expression ( n = 5 animals/group). * p < 0.05; ** p < 0.01, *** p < 0.001; **** p < 0.0001 (M, O, Q-S: ANOVA followed by post-hoc Tukey test; N: Kruskal-Wallis followed by post-hoc Dunn’s test)

Journal: Journal of Molecular Histology

Article Title: Modified citrus pectin modulates splenic immune responses and galectin expression following cisplatin treatment in Wistar rats

doi: 10.1007/s10735-026-10828-w

Figure Lengend Snippet: Analysis of galectin expression in the spleen. A – D : Galectin-1 (Gal-1) immunoreactivity. E–H : Galectin-3 (Gal-3) immunoreactivity. I–L : Galectin-9 (Gal-9) immunoreactivity. Immunolabeling is observed in both white pulp (wp) and red pulp (rp), with differences in distribution and intensity among groups: SHAM (control animals), MCP (animals treated with MCP), CIS (animals treated with cisplatin), and MCP + CIS (animals treated with MCP and cisplatin). Counterstain: Carazzi’s hematoxylin. Scale bars: 100 μm. M–O : Densitometric analysis of Gal-1, Gal-3, and Gal-9 immunoreactivity in splenic tissue. Data represent the mean ± SEM of arbitrary units (a.u.) of protein expression ( n = 5 animals/group). * p < 0.05; ** p < 0.01, *** p < 0.001; **** p < 0.0001 (M, O, Q-S: ANOVA followed by post-hoc Tukey test; N: Kruskal-Wallis followed by post-hoc Dunn’s test)

Article Snippet: E–H : Galectin-3 (Gal-3) immunoreactivity.

Techniques: Expressing, Immunolabeling, Control

Correlation analysis of galectin expression and splenic immune cell populations between CIS and MCP + CIS groups. A , B : Correlation analyses show no significant correlations between galectin expression (Gal-1, Gal-3, and Gal-9) and CD68⁺ macrophages or CD3⁺ T cells in the CIS group. C : Correlation analysis indicating positive associations between Gal-1, Gal-3, and Gal-9 expression and the CD68 + macrophage population in the MCP + CIS group. D : Correlation analysis showing a positive association between Gal-3 expression and CD3⁺ T cells in the MCP + CIS group. Correlation analyses were performed using Pearson or Spearman tests, depending on the data distribution ( n = 5 animals/group). * p < 0.05; *** p < 0.001; **** p < 0.0001

Journal: Journal of Molecular Histology

Article Title: Modified citrus pectin modulates splenic immune responses and galectin expression following cisplatin treatment in Wistar rats

doi: 10.1007/s10735-026-10828-w

Figure Lengend Snippet: Correlation analysis of galectin expression and splenic immune cell populations between CIS and MCP + CIS groups. A , B : Correlation analyses show no significant correlations between galectin expression (Gal-1, Gal-3, and Gal-9) and CD68⁺ macrophages or CD3⁺ T cells in the CIS group. C : Correlation analysis indicating positive associations between Gal-1, Gal-3, and Gal-9 expression and the CD68 + macrophage population in the MCP + CIS group. D : Correlation analysis showing a positive association between Gal-3 expression and CD3⁺ T cells in the MCP + CIS group. Correlation analyses were performed using Pearson or Spearman tests, depending on the data distribution ( n = 5 animals/group). * p < 0.05; *** p < 0.001; **** p < 0.0001

Article Snippet: E–H : Galectin-3 (Gal-3) immunoreactivity.

Techniques: Expressing